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Rodent Analgesia Service

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In some instances RARC Veterinary Services (RARC VS) may be able to provide extended release buprenorphine to your rodent models. RARC VS charges a fee for this optional service.

Charges for rodent analgesia provided by RARC VS:
Veterinary Technician Charge: $40.00/hour (billed in 15 minute increments, minimum billing time 1 hour).
Charges are based on the weight of animal.
See dosing chart for details (link at right); subject to change based on vendor pricing and availability.

What you receive:

  1. RARC VS will meet with you in advance to determine an initial dosing schedule for providing analgesia to your rodents.
  2. RARC VS will dose your rodents with an analgesic either in your laboratory space or in the vivarium.
  3. In most cases RARC VS provides an analgesia that is a formulation of sustained or extended-release buprenorphine.
  4. RARC VS refers to study design when determining whether to give buprenorphine pre- or post-procedure.

PI requirements:

  1. You must describe all procedures and subsequent analgesia (i.e. sustained release buprenorphine) in your animal-use protocol. * See language below.
  2. The PI/research staff is responsible for monitoring all animals post-procedure as per your approved protocol.
    Any signs of pica (eating of bedding or nesting material) or inappetence must be reported to your veterinary staff promptly.
  3. The PI/research staff is responsible for any non-controlled substance analgesia that rodents may require in addition to the analgesic given by RARC VS.
  4. Analgesics will only be supplied during normal RARC business hours M-F 7:30am-4pm. Pre- and post-operative dosing must be started or completed no later than 3pm to allow for adequate time of analgesic administration.
  5. The cages of all animals receiving RARC analgesia services must be clearly marked.
  6. The PI/ research staff is responsible for any sign-ups for shared equipment (e.g. bio-safety cabinets in shared spaces ) required during the time of procedure and/or time of analgesic administration.
  7. Please mail the completed RARC Veterinary Service Agreement on the right-hand side of this page to rodentanalgesia@rarc.wisc.edu. We will review the details of your request and set up a meeting, if needed. Note: your signature isn't required on the form until we meet with you.

*Add the following information to the substance admin: analgesic/anesthetic/sedation section of your protocol:

Regimen Buprenorphine SR™LAB
Drugs and Compounds Buprenorphine Sustained Release (1mg/mL)
Description Rat - 1.0-1.2 mg/kg SC into the scruff q72h
Mouse 0.5-1.0 mg/kg SC into the scruff q72h
Monitoring Plan Animals will be monitored once daily for 3 days post buprenorphine injection to look for skin reaction. (If buprenorphine will be used in conjunction with a surgical procedure, describe the surgery monitoring here as well.)
Regimen Animalgesics® for Mice & Rats
Drugs and Compounds Buprenorphine HCl extended-release injectable suspension (1.3 mg/mL)
Description Rat - 0.65 mg/kg SC into the scruff q48-72h
Mouse 03.25 mg/kg SC into the scruff q48-72h
Monitoring Plan Animals will be monitored once daily for 3 days post buprenorphine injection to look for skin reaction. (If buprenorphine will be used in conjunction with a surgical procedure, describe the surgery monitoring here as well.)

Add the following information to the complications section of your protocol:

Potential complications for either formula:

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