- What All PIs Need to Know
- ARROW Login
- ARROW Tips
- Request Grant Congruence
- Renew and Update
- 2016-058-c, Veterinary Verification and Consultation
- 1999-008-io, Non-Compliance
- 2000-013-io, Principal Investigator Status
IACUC Office Staff:
Once a PI submits a new or renewal protocol, this is the typical process:
- RARC staff assigns the protocol to the appropriate IACUC for review based on where the animals are housed. (If a veterinary pre-review is required, RARC staff routes the protocol to the appropriate veterinarian first.)
- The IACUC reviews the protocol. The committee can approve the protocol outright, require modifications, or defer review to a future meeting after the PI makes substantial revisions.
- ARROW communicates the IACUC's decision to the investigator. If a revision is required, the PI must make the necessary protocol changes in ARROW before resubmitting it for approval.
- Approval times vary widely; depending on the complexity of the protocol the submission-to-IACUC-approval process can range from 10-90 days or longer.
- Once the protocol is approved, work with animals may begin.
- An animal protocol is a contractual agreement between a principal investigator and the IACUC. Investigators must amend the protocol, and obtain IACUC approval of the changes, before performing new procedures, using new animals, or allowing new lab members to work with animals. Some changes may be eligible for Veterinary Verification and Consultation (VVC). See policy 2016-058-c or contact your veterinarian to begin the process.
- Once every year, investigators must complete a brief annual update in ARROW to maintain the active status of their protocol. PIs are notified when the update is due.
- A de novo protocol submission and IACUC review is required every three years. The renewal process is completed within ARROW, and PIs are notified when upcoming renewals are due.